As a physician with over ten years of clinical experience, I often meet patients who are curious about regenerative therapies for sexual health. One of the most frequently asked about treatments today is the Priapus Shot®, commonly known as the P‑Shot. At Dr. SNA Clinic, we provide advanced P‑Shot treatment in London for men seeking safe, evidence‑based solutions to erectile dysfunction and penile health concerns.
This article will explain the science behind the P‑Shot, its potential benefits, safety considerations, and what patients can realistically expect.
Understanding the Science Behind PRP
Platelet‑rich plasma is not unique to sexual medicine. For years, PRP has been used in orthopedics, dermatology, and sports medicine to accelerate healing in tendons, ligaments, and skin. The principle is simple: platelets contain growth factors that stimulate tissue repair and regeneration.
When applied to erectile dysfunction (ED), PRP is injected directly into the penile tissue. The goal is to:
- Stimulate angiogenesis (new blood vessel formation).
- Enhance nerve regeneration for improved sensitivity.
- Support smooth muscle repair within the corpora cavernosa.
A systematic review published in Sexual Medicine Reviews (2023) concluded that PRP shows promise in preclinical and early clinical studies for ED, though larger randomized trials are still needed.
How the P‑Shot Procedure Works
The treatment typically follows these steps:
- Blood Draw: A small sample of your blood is taken.
- PRP Preparation: The blood is spun in a centrifuge to isolate platelet‑rich plasma.
- Local Anesthesia: Numbing cream or injection is applied to minimize discomfort.
- Injection: PRP is carefully injected into specific areas of the penis.
- Recovery: Patients usually resume normal activities within 24 hours.
The entire process takes about 30–45 minutes and is performed in a clinic setting.
Potential Benefits of the P‑Shot
Patients often ask: “What can I realistically expect?” Based on current evidence and clinical experience, possible benefits include:
- Improved Erectile Function: Some men report stronger, more sustainable erections.
- Enhanced Sensitivity: Increased penile sensation may improve sexual satisfaction.
- Better Blood Flow: PRP may support vascular health in penile tissue.
- Adjunct to Other Therapies: It can complement medications like PDE5 inhibitors (Viagra, Cialis).
A meta‑analysis of PRP for ED (2024, PLOS One) found that while outcomes varied, several trials reported significant improvements in erectile function scores compared to baseline.
Safety and Risks
Like any medical procedure, the P‑Shot carries risks. The Cleveland Clinic notes that while PRP is generally safe, side effects may include:
- Bruising or swelling at the injection site.
- Temporary pain or discomfort.
- Rare cases of infection.
Importantly, the P‑Shot is still considered experimental. There is not yet enough long‑term data to confirm its effectiveness or durability. Patients should approach the treatment with realistic expectations.
Who Might Benefit from the P‑Shot?
The P‑Shot may be considered for:
- Men with mild to moderate erectile dysfunction.
- Those who cannot tolerate oral medications.
- Patients seeking a natural, regenerative approach.
- Men interested in adjunctive therapy alongside lifestyle changes.
It is not a guaranteed cure for ED, and results vary widely.
Patient FAQs
1. Is the P‑Shot painful?
Most patients experience minimal discomfort thanks to local anesthesia.
2. How soon will I see results?
Some men notice changes within weeks, while others require multiple sessions.
3. How long do results last?
Evidence is limited, but improvements may last several months. Maintenance treatments are sometimes recommended.
4. Where can I get the P‑Shot in London?
You can book directly at Dr. SNA Clinic. Visit our P‑Shot treatment London UK for details.
Ethical and Trust Considerations
As a doctor, I emphasize transparency:
- The P‑Shot is promising but not yet mainstream.
- Patients should be informed about both potential benefits and limitations.
- Clinics must avoid exaggerated claims and provide evidence‑based guidance.
Building trust means acknowledging uncertainty while offering compassionate, professional care.
The Priapus Shot (P‑Shot) represents an exciting frontier in regenerative medicine for men’s sexual health. By harnessing the body’s own healing factors, PRP injections may improve erectile function and penile sensitivity. However, the treatment remains experimental, and patients should consult experienced clinicians before proceeding.
As a physician, my advice is clear: consider the P‑Shot as part of a broader treatment plan, including lifestyle changes, medical therapies, and open communication with your healthcare provider.
References
- Poulios E, Mykoniatis I, Pyrgidis N, et al. Platelet‑rich plasma for the treatment of erectile dysfunction: a systematic review of preclinical and clinical studies. Sexual Medicine Reviews. 2023.
- Cleveland Clinic. Priapus Shot (P‑Shot): PRP, How It Works, Benefits & Risks. Updated 2024.
PLOS One. Efficacy of platelet‑rich plasma in the treatment of erectile dysfunction: meta‑analysis of clinical trials. 2024.





